Principal Investigator: Joan Greve, Ph.D.

PRINCIPAL INVESTIGATOR

JOAN M. GREVE, Ph.D.

My road to academia has been atypical. Here in pictorial format:

road

SCIENTIFIC EXPERIENCE (Doing great science is always the primary motivator!)
My undergraduate degree at the University of Washington immersed me in bioengineering research, resulted in three peer-reviewed publications, and shapes my vision of undergraduate bioengineering education.

My time as a Research Associate at Genentech, Inc. (GNE) is when I was introduced to and gained expertise in preclinical MRI and models. My passion for learning and applying imaging might best be reflected by the fact that within nine months of being introduced to preclinical MRI, my work was accepted as a platform presentation.

I wanted to be prepared to contribute to the ambition of using preclinical imaging to bridge from research to the clinic. Therefore, I chose to focus on imaging in graduate school at Stanford University. My work was one of the first to combing MRI and computational fluid dynamic modeling in preclinical models. In addition, my extensive experience had prepared me for an unusual situation, viz. leading the small animal MRI lab. I provided the imaging leadership for approximately fifteen researchers from across the university resulting in nine peer-reviewed publications spanning a plethora of topics. I remained associated with GNE as a Visiting Scientist.

Following graduate school, my goal of returning to GNE to lead the MRI lab as a Scientist came to fruition. I led the MRI preclinical research group for five years, during which time our team studied: abdominal aortic aneurysm, stroke, Alzheimer’s, amyotrophic lateral sclerosis, hepatocellular carcinoma, glioblastoma multiforme, medulloblastoma. I also had the remarkable experience of providing leadership for four years on a Project Team that successfully translated an antibody to treat Alzheimer’s disease from the bench into clinical trials.

The latter experience led me to a career in Scientific Program Management at the Allen Institute for Brain Science where I partnered with a subject matter expert in neural coding.

Although a good experience to have, I am driven by the enjoyment that comes from addressing important scientific questions that hold the potential for treating unmet medical needs and which are best answered using complex imaging systems and a team of highly-motivated cross-functional researchers. Therefore, I am elated to be joining Michigan’s Biomedical Engineering department as an Assistant Professor. My goal is to continue my leadership in preclinical imaging, mentor the next generation of biomedical engineers, and collaborate with labs whose questions of interest would benefit from preclinical imaging.

MANAGERIAL EXPERIENCE (Because great teams are critical for doing great science!)
I have led two preclinical MRI labs.

Between the two, I have, personally, taught MRI data acquisition, rudimentary problem solving of biology or technology based problems, and image analysis to nearly two dozen researchers of varying levels and from disparate educational backgrounds.

I have direct-line or matrix managed up to ten imaging researchers with training ranging from B.S. to Ph.D.+10 years of experience.

Undergraduate research I directed as a graduate student received awards.

I was an advisor, Genentech sponsor, and thesis committee member for a Stanford bioengineering graduate student who went onto a successful post-doctoral fellowship and now professorship. Our work also earned awards.